Phospholamban deficiency does not compromise exercise capacity
نویسندگان
چکیده
منابع مشابه
Phospholamban deficiency does not compromise exercise capacity.
Deficiency of phospholamban (PLB) results in enhancement of basal murine cardiac function and an attenuated response to β-adrenergic stimulation. To determine whether the absence of PLB also reduces the reserve capacity of the murine cardiovascular system to respond to stress, we evaluated the heart rate (HR), blood pressure, and metabolic responses of PLB-deficient (PLB-/-) mice to graded trea...
متن کاملIron deficiency does not compromise the diagnosis of high HbA(2) β thalassemia trait.
Hemoglobinopathies are the only genetic disease in which it is possible to detect carriers using hematologic findings rather than DNA analysis. Complete screening is based on the detection of red cell indices, HbA2, HbF and hemoglobin variant values. The classical phenotype of heterozygous b-thalassemia includes an elevated HbA2 level (3.4-6.0%), a relatively high red cell count, a markedly red...
متن کاملFatty acid translocase/CD36 deficiency does not energetically or functionally compromise hearts before or after ischemia.
BACKGROUND Evidence from humans suggests that fatty acid translocase (FAT)/CD36 deficiency can lead to functionally and/or energetically compromised hearts, but the data are equivocal, and the subject remains controversial. In this report we assessed the contribution of FAT/CD36 to overall fatty acid oxidation rates in the intact heart and determined the effect of FAT/CD36 on energy metabolism ...
متن کاملAerobic exercise does not compromise muscle hypertrophy response to short-term resistance training.
This study tested the hypothesis that chronic aerobic and resistance exercise (AE+RE) would elicit greater muscle hypertrophy than resistance exercise only (RE). Ten men (25 ± 4 yr) performed 5 wk unilateral knee extensor AE+RE. The opposing limb was subjected to RE. AE completed 6 hr prior to RE consisted of ~45 min one-legged cycle ergometry. RE comprised 4 × 7 maximal concentric-eccentric kn...
متن کاملLEARNING ARTHROSCOPIC ROTATOR CUFF Repair Does Not Compromise Patient
Purpose: Arthroscopic rotator cuff (RC) repair is reported to have a steep learning curve with rapid decrease in rotator cuff repair time (RCRT) during a surgeon’s first 10 cases. Faster surgery may represent learning; however, faster surgery does not represent better surgery. The purpose of this study is to evaluate clinical outcome (rather than RCRT) during the learning phase of arthroscopic ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: American Journal of Physiology-Heart and Circulatory Physiology
سال: 1999
ISSN: 0363-6135,1522-1539
DOI: 10.1152/ajpheart.1999.276.4.h1172